PEOPLE: CURRENT LAB MEMBERS

Lei Huang, PhD
Postdoctoral Fellow
Department of Chemistry and Chemical Biology
Harvard University
12 Oxford St.
Cambridge, MA 02138
Tel: (617) 496-4368
Fax: (617) 384-9228
leihuang@fas.harvard.edu
Home page: http://www.people.fas.harvard.edu/~leihuang/

Research Summary

I study theoretical biophysics and soft material by theory and simulations. Currently I am working on protein folding. Specifically, I am trying to improve force field of protein as well as study protein folding dynamics.

Education

08/2004-05/2008 Ph.D., Chemistry, The University of Texas at Austin
09/2001-07/2004 M.S., polymer physics, University of Science & Technology of China, China
09/1996-07/2001 B.E., polymer physics, University of Science & Technology of China, China

Publications

1. Huang L and Makarov DE, Translocation of a knotted polypeptide through a pore, JOURNAL OF CHEMICAL PHYSICS 129(12): Art. No. 121107 SEPT 30 2008
2. Huang L and Makarov DE, The rate constant of polymer reversal inside a pore, JOURNAL OF CHEMICAL PHYSICS 128(11): Art. No. 114903 MAR 19 2008
3. Huang L and Makarov DE, Langevin dynamics simulations of the diffusion of molecular knots in tensioned polymer chains, JOURNAL OF PHYSICAL CHEMISTRY A 111 (41): 10338-10344 OCT 18 2007
4. Kirmizialtin S, Huang L and Makarov DE, Computer simulations of protein translocation, PHYSICA STATUS SOLIDI B-BASIC SOLID STATE PHYSICS 243 (9): 2038-2047 JUL 2006
5. Li PC, Huang L and Makarov DE, Mechanical unfolding of segment-swapped protein G dimer: Results from replica exchange molecular dynamics simulations, JOURNAL OF PHYSICAL CHEMISTRY B 110 (29): 14469-14474 JUL 27 2006
6. Huang L and Makarov DE, On the calculation of absolute free energies from molecular-dynamics or Monte Carlo data, JOURNAL OF CHEMICAL PHYSICS 124 (6): Art. No. 064108 FEB 14 2006
7. Huang L, Kirmizialtin S and Makarov DE, Computer simulations of the translocation and unfolding of a protein pulled mechanically through a pore, JOURNAL OF CHEMICAL PHYSICS 123 (12): Art. No. 124903 SEP 22 2005
8. Kirmizialtin S, Huang L and Makarov DE, Topography of the free-energy landscape probed via mechanical unfolding of proteins, JOURNAL OF CHEMICAL PHYSICS 122 (23): Art. No. 234915 JUN 15 2005
9. Huang L, Ma XJ and Liang HJ, What is the origin of those common structures of protein-model chains?, POLYMER 47 (5): 1755-1762 FEB 22 2006
10. Li XJ, Ma XJ, Huang L and Liang HJ, Developing coarse-grained force fields for cis-poly(1,4-butadiene) from the atomistic simulation, POLYMER 46 (17): 6507-6512 AUG 8 2005
11. Sun DC, Huang L and Liang HJ, Unstable inverted phases of di- and tri-block copolymers on solution-casting films, MACROMOLECULAR RESEARCH 13 (2): 152-155 APR 2005
12. Xu BS, Huang L and Liang HJ, Thermodynamic behaviors of polyampholytes at low temperatures, JOURNAL OF CHEMICAL PHYSICS 121 (15): 7494-7500 OCT 15 2004
13. He XH, Liang HJ, Huang L and Pan CY, Complex Microstructures of Amphiphilic Diblock Copolymer in Dilute Solution, JOURNAL OF PHYSICAL CHEMISTRY B 108 (5): 1731-1735 FEB 5 2004
14. Huang L, He XH, He TB and Liang HJ, A cunning strategy in design of polymeric nanomaterials with novel microstructures, JOURNAL OF CHEMICAL PHYSICS 119 (23): 12479-12486 DEC 15 2003
15. Huang L, He XH, Wang YY, Chen HN and Liang HJ, Phase transitions of short chains at ultralow temperature, JOURNAL OF CHEMICAL PHYSICS 119 (4): 2432-2438 JUL 22 2003
16. He XH, Huang L, Liang HJ and Pan CY, Localizations of junction points of ABC 3-miktoarm star terpolymers, JOURNAL OF CHEMICAL PHYSICS 118 (21): 9861-9863 JUN 1 2003
17. Huang L, He XH, Huang LS and Liang HJ, Computer simulation on the self-assembly of associating polymers, POLYMER 44 (6): 1967-1972 MAR 2003
18. He XH, Huang L, Liang HJ and Pan CY, Self-assembly of star block copolymers by dynamic density functional theory, JOURNAL OF CHEMICAL PHYSICS 116 (23): 10508-10513 JUN 15 2002