PEOPLE: CURRENT LAB MEMBERS

Konstantin Zeldovich, PhD
Postdoctoral Fellow
Department of Chemistry and Chemical Biology
Harvard University
12 Oxford St. Box 35
Cambridge, MA 02138
Tel: (617) 496-4368
Fax: (617) 384-9228
kzeldov@fas.harvard.edu

Research Summary

My research interests are in the area of theoretical soft condensed matter physics and biophysics. Currently, I am working on computer simulations of molecular evolution with the emphasis on sequence/structure relationship in the newly emerging molecules.

1. K.B. Zeldovich, P. Chen, E.I. Shakhnovich. Protein stability imposes limits on organism complexity and speed of molecular evolution. PNAS , 104 (41): 16152-16157 (2007)
2. K.B. Zeldovich, P. Chen, B.E. Shakhnovich, E.I. Shakhnovich. A first-principles model of early evolution: Emergence of gene families, species and preferred protein folds. PLoS Computational Biology, 3 (7): e139 (2007)
3. S. Wallin, K.B. Zeldovich, E.I. Shakhnovich. The folding mechanics of a knotted protein. Journal of Molecular Biology 368: 884-893 (2007)
4. I.N. Berezovsky, K.B. Zeldovich, E.I. Shakhnovich. Positive and negative design in stability and thermal adaptation of natural proteins, PLoS Computational Biology 3 (3): e52 (2007)
5. K.B. Zeldovich, I.N. Berezovsky, E.I. Shakhnovich. Protein and DNA sequence determinants of thermophilic adaptation, PLoS Computational Biology 3 (1): e5 (2007)
6. D.B. Lukatsky, K.B. Zeldovich, E.I. Shakhnovich. Statistically enhanced self-attraction of random patterns. Physical Review Letters 97 (17): 178101 (2006)
7. O. Campas, Y. Kafri, K.B. Zeldovich, J. Casademunt, J.-F. Joanny. Collective dynamics of interacting molecular motors. Physical Review Letters 97 (3): 038101 (2006)
8. K.B. Zeldovich, I.N. Berezovsky, E.I. Shakhnovich, Physical origins of protein superfamilies. Journal of Molecular Biology 357 (4): 1335-1343 (2006)
9. K.B. Zeldovich, J.-F. Joanny, J. Prost. Motor proteins transporting cargos. European Physical Journal E 17 (2): 155-163 (2005)
10. N. Minc, P. Bokov, K.B. Zeldovich, C. Futterer, J.-L. Viovy, K.D. Dorfman. Motion of single long DNA molecules through arrays of magnetic columns. Electrophoresis 26 (2): 362-375 (2005)
11. C. Leduc, O. Campas, K.B. Zeldovich, A. Roux, P. Jolimaitre, L. Bourel-Bonnet, B. Goud, J.-F. Joanny, P. Bassereau, J. Prost. Cooperative extraction of membrane nanotubes by molecular motors. Proc. Natl. Acad. Sci. USA 101 (49): 17096-17101 (2004)
12. A. Dornier, L. Busoni, K.B. Zeldovich, B. Guirao, G. Robin, G. Cappello, J. Prost. Kinesin step without external force takes less than 70 microseconds. The Journal of Biological Physics and Chemistry 4 (2): 50-63 (2004)
13. E.N. Govorun, K.B. Zeldovich, A.R. Khokhlov. Structure of charged poly(propylene imine) dendrimers: Theoretical investigation. Macromolecular Theory and Simulations 12 (9): 705-713 (2003)
14. I.I. Potemkin, K.B. Zeldovich, A.R. Khokhlov. Statistical physics of associating polyelectrolyte solutions. Polymer Science Ser. C 42 (2): 154-171 (2000)
15. A.R. Khokhlov, K.B. Zeldovich. Osmotically active and osmotically passive counterions in inhomogeneous polyelectrolyte gels, Abstracts of Papers of The American Chemical Society 219: 353-POLY Part 2 (2000)
16. K.B. Zeldovich, A.R. Khokhlov. Role of ion pairs in surface-charge overcompensation in polyelectrolyte adsorption and polyelectrolyte multilayer formation. Abstracts of Papers of The American Chemical Society 219: 57-COLL Part 1 (2000)
17. K.B. Zeldovich, A.R. Khokhlov. Osmotically active and passive counterions in inhomogeneous polymer gels. Macromolecules 32 (10): 3488-3494 (1999)
18. A.R. Khokhlov, E.E. Makhaeva, K.B. Zeldovich. Interplay of ionic and nonionic interactions in weakly charged polyelectrolytes. Macromolecular Symposia 117: 89-98 (1997)
19. K.B. Zeldovich, E.E. Dormidontova, A.R. Khokhlov, T.A. Vilgis. Microphase separation transition for polyelectrolyte gels in poor solvents. Journal de Physique II 7 (4): 627-635 (1997)